Withdrawal
When an organism (does not have to be a human; can be another type of animal) becomes addicted to a substance, and then they are prevented from having that substance for an extended period of time, they go through a period of withdrawal. This period of withdrawal involves feelings of discomfort and distress. For example, a person addicted to cocaine may experience long periods of nausea, vomiting, cold sweats, headaches, mood swings, and other very uncomfortable feelings. Both physiological and psychological aspects are involved in withdrawal.