Lennox-Gastaut Syndrome (LGS)

Lennox-Gastaut Syndrome (LGS) also known as childhood epileptic encephalopathy, is characterized by a number of seizure types (involving stiffening and dropping), intellectual disability (not always), and electroencephalography abnormal findings such as slow spike waves. It often develops from three to five years old and may persist into adulthood. There are different causes such as brain infections, injury, genetics, and prenatal complications. Around 10% of those who are affected have unknown causes.

Generally, the seizures cannot be treated with medications. There have been reports that a ketogenic diet can reduce the seizures for up to 50%. LGS was first independently described by William G. Lennox, an American neurologist, and Henri Gastaut, a French neurologist.