Klippel-Trenaunay-Weber Syndrome

Klippel-Trenaunay-Weber syndrome is the former name of Klippel-Trenaunay syndrome; it is also sometimes referred to as angioosteohypertrophy syndrome and hemangiectatic hypertrophy.

The symptoms of this rare congenital condition is a triad of varicose veins, port-wine stain, and soft and bony tissue hypertrophy of a limb (may lead to shrinking or gigantism of the affected extremity). Patients may also have health concerns regarding their lymph system. The symptoms may be managed but there is no cure for this syndrome which was first described by Maurice Klippel and Paul Trenaunay, French physicians, in 1900. Frederick Parkes Weber, a German-British physician, also described similar yet not identical cases in 1907 and 1918.