Inhibitory Postsynaptic Potential

An Inhibitory postsynaptic potential is a neural reaction that makes it less likely for a neuron to fire repeatedly. This complex electrochemical reaction depends on many factors such as the size and type of neurotransmitters involved. What this actually means is that some nerves can be stimulated once but are not subject to repeated firing for the same stimulus.

For example, if you put your hand into icy water your nervous system will react quickly and cause you withdraw your hand. After this happens, you can put your hand back into the water and although you will still feel the cold you will not experience the reflex of hand withdrawal.