Gardner-Diamond Syndrome

Gardner-Diamond syndrome, also known as psychogenic purpura or autoerythrocyte sensitization syndrome, is characterized by foreseeable bruising as preceded by warmth and pain at the concerned body part. The skin lesions are preceded by emotional trauma and acute stress. This rare condition is most commonly reported by women but there were also isolated cases concerning men. This was described Gardner and Diamond with their paper publication in 1955.

This is difficult to diagnose as the etiological mechanism is not fully known. This is most likely caused by psychological factors as the most effective treatment is psychotherapy. Other sources explain that this syndrome is an autoimmune disease which means that the symptoms are caused by both genetic and environmental factors.